E2F-2 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Cell Growth and Death, Cancers, Transcription

Description:
Transcription factor E2F2 (E2F-2) is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F-2 complex functions in the control of cell-cycle progression from G1 to S phase. E2F-2 binds specifically to RB1 protein in a cell-cycle dependent manner.

Alternate Names: Transcription factor E2F2, E2F-2, E2F2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q14209

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human E2F-2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.