E2F-5 Polyclonal Antibody

Background:
E2F transcription factor 5(E2F5) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter

Alternative Names:
E2F5, Transcription factor E2F5, E2F-5

Immunogen: The antiserum was produced against synthesized peptide derived from human E2F-5. AA range:93-142

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 36

GeneID: E2F5

Storage: -20°C/1 year

NOTE: For Research Use Only