E2F3 antibody (clone 5F7), anti-human
€435.00
In stock
SKU
AC-AT1834a
Catalog Number: AC-AT1834a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT1834a">Request Information
Background:
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Other Names:
Transcription factor E2F3, E2F-3, E2F3, KIAA0075
Antigen Type:
Recombinant Protein
Gene Name: E2F3
Gene ID: 1871
NCBI Accession: NP_001230005.1;NP_001940.1
Primary Accession: O00716
Other Accession: NM_001949
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Other Names:
Transcription factor E2F3, E2F-3, E2F3, KIAA0075
Antigen Type:
Recombinant Protein
Gene Name: E2F3
Gene ID: 1871
NCBI Accession: NP_001230005.1;NP_001940.1
Primary Accession: O00716
Other Accession: NM_001949
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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