E2F3 Polyclonal Antibody

Background:
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
E2F3, E2F-3

Immunogen: A synthetic peptide of human E2F3 (NP_001230005.1).

Swissprot: O00716
Gene ID: 1871

Calculated MW: 37 kDa/49 kDa
Observed MW: 53 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.