E2F3 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP14598c
Catalog Number: AC-AP14598c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34586
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34586
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Other Names:
Transcription factor E2F3, E2F-3, E2F3, KIAA0075
Target/Specificity:
This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3.
Antigen Region:
151-180
Antigen Type: Synthetic Peptide
Gene Name: E2F3
Gene ID: 1871
Primary Accession: O00716
NCBI Accession: NP_001230005.1;NP_001940.1
Other Accession: O35261; NP_001940.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Other Names:
Transcription factor E2F3, E2F-3, E2F3, KIAA0075
Target/Specificity:
This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3.
Antigen Region:
151-180
Antigen Type: Synthetic Peptide
Gene Name: E2F3
Gene ID: 1871
Primary Accession: O00716
NCBI Accession: NP_001230005.1;NP_001940.1
Other Accession: O35261; NP_001940.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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