E2F5 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP9003a
Catalog Number: AC-AP9003a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23726
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23726
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
Other Names:
Transcription factor E2F5, E2F-5, E2F5
Target/Specificity:
This E2F5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.
Antigen Region:
66-93
Antigen Type: Synthetic Peptide
Gene Name: E2F5
Gene ID: 1875
Primary Accession: Q15329
NCBI Accession: NP_001077057.1;NP_001077058.1;NP_001942.2
Other Accession: Q62814; Q61502; Q6DE14; Q8R0K9; Q16254
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
Other Names:
Transcription factor E2F5, E2F-5, E2F5
Target/Specificity:
This E2F5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.
Antigen Region:
66-93
Antigen Type: Synthetic Peptide
Gene Name: E2F5
Gene ID: 1875
Primary Accession: Q15329
NCBI Accession: NP_001077057.1;NP_001077058.1;NP_001942.2
Other Accession: Q62814; Q61502; Q6DE14; Q8R0K9; Q16254
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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