E6AP polyclonal, anti-human, mouse antibody
€275.00
In stock
SKU
AC-ABV10567-100
Catalog Number: AC-ABV10567-100
Size: 100 µl
Host: Rabbit IgG
Applications: WB, IP
Datasheet
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Size: 100 µl
Host: Rabbit IgG
Applications: WB, IP
Datasheet
Request Information
Background:
E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.
Other Names:
E6AP, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein, UBE3A, Ubiquitin-protein ligase E3A, AS, Angelman Syndrome, ANCR
Primary Accession: Q05086
Other Accession: NP_000453.2
Gene Name: UBE3A (HGNC:12496)
Gene ID: 7337
E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.
Other Names:
E6AP, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein, UBE3A, Ubiquitin-protein ligase E3A, AS, Angelman Syndrome, ANCR
Primary Accession: Q05086
Other Accession: NP_000453.2
Gene Name: UBE3A (HGNC:12496)
Gene ID: 7337
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