EAAT2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
SLC1A2 is also known as EAAT2 or GLT-1. This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.

Description:
Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 2 (SLC1A2) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
EAA2_HUMAN antibody, EAAT2 antibody, Excitatory amino acid transporter 2 antibody, Excitotoxic amino acid transporter 2 antibody, Glial high affinity glutamate transporter antibody, GLT 1 antibody, GLT1 antibody, Glutamate aspartate transporter II antibody, Glutamate transporter 1 antibody, Glutamate/aspartate transporter II antibody, Slc1a2 antibody, Sodium dependent glutamate aspartate transporter 2 antibody, Sodium-dependent glutamate/aspartate transporter 2 antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 2 antibody, Solute carrier family 1 glial high affinity glutamate transporter member 2 antibody, Solute carrier family 1 member 2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human EAAT2 recombinant protein (Position: T461-K574). Human EAAT2 shares 96% amino acid (aa) sequence identity with both mouse and rat EAAT2.E.coli-derived human EAAT2 recombinant protein (Position: T461-K574). Human EAAT2 shares 96% amino acid (aa) sequence identity with both mouse and rat EAAT2.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.