EAAT3 polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
Solute carrier family 1 member 1, also called SLC1A1, is a protein that in humans is encoded by the SLC1A1 gene. By Southern analysis of a panel of human/rodent somatic cell hybrids and by fluorescence in situ hybridization(FISH), this gene is mapped to 9p24.2. This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are though to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.

Description:
Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 3 (SLC1A1) detection. Tested with WB in Mouse, Rat.

Synonyms:
EAA3_HUMAN antibody, EAAC 1 antibody, EAAC1 antibody, EAAT 3 antibody, Excitatory amino acid carrier 1 antibody, Excitatory amino acid carrier1 antibody, Excitatory amino acid transporter 3 antibody, Excitatory amino acid transporter3 antibody, Excitatory amino-acid carrier 1 antibody, GLUTAMATE TRANSPORTER, HIGH-AFFINITY antibody, MEAAC 1 antibody, MEAAC1 antibody, Neuronal and epithelial glutamate transporter antibody, REAAC 1 antibody, REAAC1 antibody, Slc1 a1 antibody, Slc1a 1 antibody, SLC1A1 antibody, Sodium dependent glutamate/aspartate transporter 3 antibody, Sodium-dependent glutamate/aspartate transporter 3 antibody, Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody, SOLUTE CARRIER FAMILY 1(NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 antibody, Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody, Solute carrier family 1 member 1 antibody, Solute carrier family 1, member 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of mouse EAAT3(10-27aa DWRRFLRNHWLLLSTVAA), identical to the related rat sequence.A synthetic peptide corresponding to a sequence at the N-terminus of mouse EAAT3(10-27aa DWRRFLRNHWLLLSTVAA), identical to the related rat sequence.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.