EAF2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8722
Background:
EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.
Alternative Name:
ELL-associated factor 2, Testosterone-regulated apoptosis inducer and tumor suppressor protein, EAF2, TRAITS, BM-040
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: EAF2 polyclonal antibody detects endogenous levels of EAF2 protein.
Immunogen:
Recombinant full length Human EAF2.
MW: ~ 29kDa
Swis Prot.: Q96CJ1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.
Alternative Name:
ELL-associated factor 2, Testosterone-regulated apoptosis inducer and tumor suppressor protein, EAF2, TRAITS, BM-040
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: EAF2 polyclonal antibody detects endogenous levels of EAF2 protein.
Immunogen:
Recombinant full length Human EAF2.
MW: ~ 29kDa
Swis Prot.: Q96CJ1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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