EARS2 Polyclonal Antibody

Background:
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.

Research Area: Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Synonyms:
3230401I01Rik, AL024049, COXPD12, EARS 2, ears2, GluRS, Glutamate--tRNA ligase, Glutamyl tRNA synthetase 2 mitochondrial, mitochondrial, mKIAA1970, MSE1, Probable glutamyl tRNA synthetase, mitochondrial , Probable glutamyl-tRNA synthetase, RGD1307904, SYEM

Immunogen: Synthetic peptide of human EARS2

Swissprot: Q5JPH6
Gene Accession: NP001077083

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.