EAT-2 rabbit polyclonal, anti-human, mouse, rat

Backgroud: By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008],function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.,similarity:Contains 1 SH2 domain.,subunit:Binds to the phosphorylated receptors CD84, CD150, CD229 and CD244. Does not bind to non-phosphorylated CD150.,

Synonyms: SH2D1B, EAT2, SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2

Gene Name: SH2D1B

Gene ID: 117157

SwissProt ID: O14796

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.