ECE2 Polyclonal Antibody

Background:
Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Research Area: Cardiovascular, Neuroscience, Signal Transduction

Synonyms:
ECE 2, ECE-2, ECE2, ECE2, Endothelin converting enzyme 2, Endothelin-converting enzyme 2 region, Hypothetical protein MGC2408, KIAA0604, MGC17664, MGC78487

Immunogen: Recombinant protein of human ECE2

Swissprot: O60344
Gene Accession: BC005835

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.