ECE2 Polyclonal Antibody

Background:
This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

Research Area: Cardiovascular, Neuroscience, Signal transduction

Synonyms:
ECE 2, ECE-2, ECE2, ECE2, Endothelin converting enzyme 2, Endothelin-converting enzyme 2 region, Hypothetical protein MGC2408, KIAA0604, MGC17664, MGC78487

Immunogen: Fusion protein of human ECE2

Swissprot: O60344
Gene Accession: BC005835

Calculated MW: 100 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.