ECH1 antibody (clone 5G8), anti-human
€435.00
In stock
SKU
AC-AT1848a
Catalog Number: AC-AT1848a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB
Request Information AC-AT1848a">Request Information
Background:
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Other Names:
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial, 533-, ECH1
Antigen Type:
Recombinant Protein
Gene Name: ECH1 (HGNC:3149)
Gene ID: 1891
NCBI Accession: NP_001389.2
Primary Accession: Q13011
Other Accession: NM_001398
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Other Names:
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial, 533-, ECH1
Antigen Type:
Recombinant Protein
Gene Name: ECH1 (HGNC:3149)
Gene ID: 1891
NCBI Accession: NP_001389.2
Primary Accession: Q13011
Other Accession: NM_001398
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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