ECSIT Polyclonal Antibody

Background:
Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).

Research Area: Cancer, Immunology, Signal transduction

Synonyms:
Ecsit, ECSIT homolog, ECSIT protein, ECSIT, Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathways, Likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved, Protein SITPEC, Signaling intermediate in Toll pathway evolutionarily conserved, SITPEC, SITPEC protein

Immunogen: Fusion protein of human ECSIT

Swissprot: Q9BQ95
Gene Accession: BC000193

Calculated MW: 49 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.26 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.