EDA2R Polyclonal Antibody

Background:
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.

Research Area: Cancer, Cell Biology, Signal Transduction, Stem Cells

Synonyms:
9430060M22Rik, Ectodysplasin A2 isoform receptor, Ectodysplasin A2 receptor, EDA A2R, EDA-A2 receptor, EDA2R, EDAA2R, MGC124099, OTTMUSP00000019574, OTTMUSP00000019575, RP23-188N15.1, TNFRSF27, TNR27, Tumor necrosis factor receptor superfamily member 27, Tumor necrosis factor receptor superfamily member XEDAR, X linked ectodysplasin A2 receptor, X linked ectodysplasin receptor, X-linked ectodysplasin-A2 receptor, XEDAR

Immunogen: Recombinant protein of human EDA2R

Swissprot: Q9HAV5
Gene Accession: BC034919

Calculated MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15291/sc-366134