EDA2R polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP18402b
Catalog Number: AC-AP18402b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38447
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38447
Applications: WB
Datasheet
Request Information
Background:
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq].
Other Names:
Tumor necrosis factor receptor superfamily member 27, X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, TNFRSF27, XEDAR
Target/Specificity:
This EDA2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-297 amino acids from the C-terminal region of human EDA2R.
Antigen Region:
267-297
Antigen Type: Synthetic Peptide
Gene Name: EDA2R
Gene ID: 60401
Primary Accession: Q9HAV5
NCBI Accession: NP_001186616.1;NP_001229239.1;NP_068555.1
Other Accession: NP_068555.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq].
Other Names:
Tumor necrosis factor receptor superfamily member 27, X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, TNFRSF27, XEDAR
Target/Specificity:
This EDA2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-297 amino acids from the C-terminal region of human EDA2R.
Antigen Region:
267-297
Antigen Type: Synthetic Peptide
Gene Name: EDA2R
Gene ID: 60401
Primary Accession: Q9HAV5
NCBI Accession: NP_001186616.1;NP_001229239.1;NP_068555.1
Other Accession: NP_068555.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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