EDAR Polyclonal Antibody

Background:
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Research Area: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
Anhidrotic ectodysplasin receptor 1, DL, Downless (mouse) homolog, Downless homolog, Downless mouse homolog of, ECTD10A, ECTD10B, Ectodermal dysplasia receptor, Ectodysplasin 1 anhidrotic receptor, Ectodysplasin A receptor, Ectodysplasin A1 isoform receptor, Ectodysplasin-A receptor, ED 1R, ED 3, ED 5, ED1R, ED3, ED5, EDA 1R, EDA 3, EDA A1 receptor, EDA A1R, EDA-A1 receptor, EDA1R, EDA3, Edar, EDAR, HRM1, Tumor necrosis factor receptor superfamily member EDAR

Immunogen: Synthetic peptide of human EDAR

Swissprot: Q9UNE0
Gene Accession: NP_071731

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:35-1:150

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15289/sc-15290