EDARADD Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16194b
Background:
This gene was identified by its association withectodermal dysplasia, a genetic disorder characterized by defectivedevelopment of hair, teeth, and eccrine sweat glands. The proteinencoded by this gene is a death domain-containing protein, and isfound to interact with EDAR, a death domain receptor known to berequired for the development of hair, teeth and other ectodermalderivatives. This protein and EDAR are coexpressed in epithelialcells during the formation of hair follicles and teeth. Through itsinteraction with EDAR, this protein acts as an adaptor, and linksthe receptor to downstream signaling pathways. Two alternativelyspliced transcript variants of this gene encoding distinct isoformshave been reported.
Other Names:
Ectodysplasin-A receptor-associated adapter protein, EDAR-associated death domain protein, Protein crinkled homolog, EDARADD
Gene Name: EDARADD
Gene ID: 128178
Primary Accession: Q8WWZ3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene was identified by its association withectodermal dysplasia, a genetic disorder characterized by defectivedevelopment of hair, teeth, and eccrine sweat glands. The proteinencoded by this gene is a death domain-containing protein, and isfound to interact with EDAR, a death domain receptor known to berequired for the development of hair, teeth and other ectodermalderivatives. This protein and EDAR are coexpressed in epithelialcells during the formation of hair follicles and teeth. Through itsinteraction with EDAR, this protein acts as an adaptor, and linksthe receptor to downstream signaling pathways. Two alternativelyspliced transcript variants of this gene encoding distinct isoformshave been reported.
Other Names:
Ectodysplasin-A receptor-associated adapter protein, EDAR-associated death domain protein, Protein crinkled homolog, EDARADD
Gene Name: EDARADD
Gene ID: 128178
Primary Accession: Q8WWZ3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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