EDD Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP2101c
Background:
EDD is a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22, a locus disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
Other Names:
E3 ubiquitin-protein ligase UBR5, 632-, E3 ubiquitin-protein ligase, HECT domain-containing 1, Hyperplastic discs protein homolog, hHYD, Progestin-induced protein, UBR5, EDD, EDD1, HYD, KIAA0896
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2101c was selected from the Center region of human EDD . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UBR5
Gene ID: 51366
Primary Accession: O95071
Other Accession: NP_056986
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
EDD is a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22, a locus disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
Other Names:
E3 ubiquitin-protein ligase UBR5, 632-, E3 ubiquitin-protein ligase, HECT domain-containing 1, Hyperplastic discs protein homolog, hHYD, Progestin-induced protein, UBR5, EDD, EDD1, HYD, KIAA0896
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2101c was selected from the Center region of human EDD . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UBR5
Gene ID: 51366
Primary Accession: O95071
Other Accession: NP_056986
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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