EDEM3 polyclonal, anti-human, mouse, rat antibody
€325.00
In stock
SKU
AC-ABV10459-100
Catalog Number: AC-ABV10459-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
EDEM3 belongs to the glycosyl hydrolase 47 family. It is involved in endoplasmic reticulum-associated degradation (ERAD). Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 accelerates the degradation of misfolded glycoproteins in the ER. It also accelerates the glycoprotein ERAD by proteasomes and this process depends on mannose-trimming from the N-glycans. It is most likely to have some alpha 1, 2-mannosidase activity.
Other Names:
Alpha-1, 2-mannosidase EDEM3
Primary Accession: Q9BZQ6
Gene Name: EDEM3
Gene ID: 80267
Concentration (mg/ml): 0.5 mg/ml
EDEM3 belongs to the glycosyl hydrolase 47 family. It is involved in endoplasmic reticulum-associated degradation (ERAD). Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 accelerates the degradation of misfolded glycoproteins in the ER. It also accelerates the glycoprotein ERAD by proteasomes and this process depends on mannose-trimming from the N-glycans. It is most likely to have some alpha 1, 2-mannosidase activity.
Other Names:
Alpha-1, 2-mannosidase EDEM3
Primary Accession: Q9BZQ6
Gene Name: EDEM3
Gene ID: 80267
Concentration (mg/ml): 0.5 mg/ml
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