EDG3 Polyclonal Antibody

Background:
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
EDG 3, EDG3, Endothelial differentiation G protein coupled receptor 3, Endothelial differentiation G-protein coupled receptor 3, Endothelial differentiation gene 3, Endothelial differentiation sphingolipid G protein coupled receptor 3, FLJ37523, FLJ93220, G protein coupled receptor endothelial differentiation gene 3, LPB 3, LPB3, MGC71696, OTTHUMP00000215691, S1P receptor 3, S1P receptor Edg 3, S1P receptor Edg-3, S1P receptor EDG3, S1P3, S1pr3, S1PR3, Sphingosine 1 phosphate receptor 3, Sphingosine 1 phosphate receptor Edg 3, Sphingosine 1 phosphate receptor Edg3, Sphingosine 1-phosphate receptor 3, Sphingosine 1-phosphate receptor Edg-3

Immunogen: Synthetic peptide of human S1PR3

Swissprot: Q99500
Gene Accession: NP_005217

Calculated MW: 42 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-22214/sc-22210/sc-22211/sc-16076/sc-30024