EDG8 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6144a
Background:
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction, both intracellularly as a second messenger and extracellularly as a receptor ligand. EDG8, a receptor for S1P, is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. Human, rat, and mouse EDG8 proteins possess 97% sequence identity and appear to signal via G(i/o)alpha proteins. Human EDG8 is expressed in spleen, corpus collosum, peripheral blood leukocytes, placenta, lung, aorta, and several fetal tissues. Its precise role remains to be determined.
Other Names:
Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8, S1PR5, EDG8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6144a was selected from the N-term region of human EDG8 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: S1PR5
Gene ID: 53637
Primary Accession: Q9H228
Other Accession: NP_110387
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction, both intracellularly as a second messenger and extracellularly as a receptor ligand. EDG8, a receptor for S1P, is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. Human, rat, and mouse EDG8 proteins possess 97% sequence identity and appear to signal via G(i/o)alpha proteins. Human EDG8 is expressed in spleen, corpus collosum, peripheral blood leukocytes, placenta, lung, aorta, and several fetal tissues. Its precise role remains to be determined.
Other Names:
Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8, S1PR5, EDG8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6144a was selected from the N-term region of human EDG8 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: S1PR5
Gene ID: 53637
Primary Accession: Q9H228
Other Accession: NP_110387
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review