EDN3 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11222b
Background:
The protein encoded by this gene is a member of theendothelin family. Endothelins are endothelium-derived vasoactivepeptides involved in a variety of biological functions. The activeform of this protein is a 21 amino acid peptide processed from theprecursor protein. The active peptide is a ligand for endothelinreceptor type B (EDNRB). The interaction of this endothelin withEDNRB is essential for development of neural crest-derived celllineages, such as melanocytes and enteric neurons. Mutations inthis gene and EDNRB have been associated with Hirschsprung disease(HSCR) and Waardenburg syndrome (WS), which are congenitaldisorders involving neural crest-derived cells. Four alternativelyspliced transcript variants encoding three distinct isoforms havebeen observed.
Other Names:
Endothelin-3, ET-3, Preproendothelin-3, PPET3, EDN3
Gene Name: EDN3
Gene ID: 1908
Primary Accession: P14138
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of theendothelin family. Endothelins are endothelium-derived vasoactivepeptides involved in a variety of biological functions. The activeform of this protein is a 21 amino acid peptide processed from theprecursor protein. The active peptide is a ligand for endothelinreceptor type B (EDNRB). The interaction of this endothelin withEDNRB is essential for development of neural crest-derived celllineages, such as melanocytes and enteric neurons. Mutations inthis gene and EDNRB have been associated with Hirschsprung disease(HSCR) and Waardenburg syndrome (WS), which are congenitaldisorders involving neural crest-derived cells. Four alternativelyspliced transcript variants encoding three distinct isoforms havebeen observed.
Other Names:
Endothelin-3, ET-3, Preproendothelin-3, PPET3, EDN3
Gene Name: EDN3
Gene ID: 1908
Primary Accession: P14138
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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