EDN3 antibody (clone 2A6-2A4), anti-human
€435.00
In stock
SKU
AC-AT1852a
Catalog Number: AC-AT1852a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IP, E
Request Information AC-AT1852a">Request Information
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IP, E
Request Information AC-AT1852a">Request Information
Background:
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Other Names:
Endothelin-3, ET-3, Preproendothelin-3, PPET3, EDN3
Antigen Type:
Recombinant Protein
Gene Name: EDN3
Gene ID: 1908
NCBI Accession: NP_000105.1;NP_996915.1;NP_996916.1;NP_996917.1
Primary Accession: P14138
Other Accession: BC008876
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Other Names:
Endothelin-3, ET-3, Preproendothelin-3, PPET3, EDN3
Antigen Type:
Recombinant Protein
Gene Name: EDN3
Gene ID: 1908
NCBI Accession: NP_000105.1;NP_996915.1;NP_996916.1;NP_996917.1
Primary Accession: P14138
Other Accession: BC008876
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review