EDNRB polyclonal, anti-human, mouse

EDNRB polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS7452
Catalog Number: BS7452
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Name:
ABCDS, Ednra, EDNRB, EDNRB_HUMAN, Endothelin B receptor, Endothelin B receptor precursor, Endothelin receptor Non selective type, Endothelin receptor non-selective type, Endothelin receptor type B, ET B, ET-B, ET-BR, ETB, ETBR, ETRB, Hirschsprung disease 2, HSCR, HSCR2, OTTHUMP00000018534, OTTHUMP00000178736, WS4A,

Application Dilution: WB: 1:500 - 1:2000

Specificity: EDNRB polyclonal antibody detects endogenous levels of EDNRB protein.

Immunogen:
Recombinant full length Human EDNRB.

MW: ~50 kDa

Swis Prot.: P24530

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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