EDNRB polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Endothelin receptor type B, also known as ETB is a protein that in humans is encoded by the EDNRB gene. The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for Endothelin B receptor (EDNRB) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
ABCDS antibody, Ednra antibody, Ednrb antibody, EDNRB_HUMAN antibody, Endothelin B receptor antibody, Endothelin B receptor precursor antibody, Endothelin receptor Non selective type antibody, Endothelin receptor non-selective type antibody, Endothelin receptor type B antibody, ET B antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, Hirschsprung disease 2 antibody, HSCR antibody, HSCR2 antibody, OTTHUMP00000018534 antibody, OTTHUMP00000178736 antibody, WS4A antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human EDNRB (406-439aa QSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKY), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.