EEA1 Polyclonal Antibody

Background:
Early endosome antigen 1 (EEA1) is a marker of early endosomes and has an important role in endosomal trafficking. EEA1 contains coiled-coil regions and an FYVE-type zinc finger which interacts with phosphatidylinositol-3-phosphate. EEA1 functions as a Rab5 effector, mediates endosome docking and, together with SNAREs, leads to membrane fusion.

Research Area: Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers

Synonyms:
Early endosome antigen 1, Early endosome antigen 1, 162kD, Early endosome associated protein, EEA 1, EEA1, EEA1, Endosome associated protein p162, Endosome-associated protein p162, MST105, MSTP105, ZFYVE2, Zinc finger FYVE domain containing protein 2, Zinc finger FYVE domain-containing protein 2

Immunogen: Synthetic peptide of human EEA1

Swissprot: Q15075
Gene Accession: NP003557

Calculated MW: 163 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.62 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.