EEA1 Polyclonal Antibody

Background:
Early endosome antigen 1 (EEA1) is a marker of early endosomes and has an important role in endosomal trafficking. EEA1 contains coiled-coil regions and an FYVE-type zinc finger which interacts with phosphatidylinositol-3-phosphate. EEA1 functions as a Rab5 effector, mediates endosome docking and, together with SNAREs, leads to membrane fusion.

Research Area: Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers

Synonyms:
EEA1, MST105, MSTP105, ZFYVE2

Immunogen: Recombinant fusion protein of human EEA1 (NP_003557.2).

Swissprot: Q15075
Gene ID: 8411

Calculated MW: 162 kDa
Observed MW: 175 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.