EEA1 Polyclonal Antibody

Background:
disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

Alternative Names:
EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

Immunogen: The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 162

GeneID: EEA1

Storage: -20°C/1 year

NOTE: For Research Use Only