EF-1 alpha 1/2 (Acetyl Lys146) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex| which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain| placenta| lung| liver| kidney| and pancreas| and the other isoform (alpha 2) is expressed in brain| heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes| some of which| if not all| represent different pseudogenes.

Research Area: Epigenetics and nuclear signaling

Synonyms: EF-1 α1/2 , Acetyl Lys146, Elongation factor 1-alpha 1, EF-1-alpha-1, Elongation factor Tu, EF-Tu, Eukaryotic elongation factor 1 A-1, eEF1A-1, Leukocyte receptor cluster member 7

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year