EF-G2 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013],translation, mitochondrion organization, cellular component disassembly, mitochondrial translation, ribosome disassembly, macromolecular complex disassembly, ribonucleoprotein complex disassembly, cellular macromolecular complex subunit organization, cellular macromolecular complex disassembly, macromolecular complex subunit organization,

Synonyms: GFM2, EFG2, MSTP027, Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2, Elongation factor G2, hEFG2

Gene Name: GFM2

Gene ID: 84340

SwissProt ID: Q969S9

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.