EFNA1 Polyclonal Antibody
€0.00
In stock
SKU
E-AB-60908
Catalog Number: E-AB-60908
Isotype: Rabbit IgG
Reactivity: human, mouse
Applications: WB,IHC
Datasheet, Questions? Contact us!
Isotype: Rabbit IgG
Reactivity: human, mouse
Applications: WB,IHC
Datasheet, Questions? Contact us!
Background:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
Research Area: Cardiovascular, Neuroscience, Signal Transduction
Synonyms:
EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4, ephrin-A1
Immunogen: Recombinant fusion protein of human EFNA1 (NP_004419.2).
Swissprot: P20827
Gene ID: 1942
Calculated MW: 21 kDa/23 kDa
Observed MW: 21-23 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
Research Area: Cardiovascular, Neuroscience, Signal Transduction
Synonyms:
EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4, ephrin-A1
Immunogen: Recombinant fusion protein of human EFNA1 (NP_004419.2).
Swissprot: P20827
Gene ID: 1942
Calculated MW: 21 kDa/23 kDa
Observed MW: 21-23 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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