EFNA2 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP50698
Background:
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
Other Names:
Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, HEK7-L, EFNA2, EPLG6, LERK6
Antigen Type: Synthetic Peptide
Antigen Type: EFNA2
Gene ID: 1943
Primary Accession: O43921
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
Other Names:
Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, HEK7-L, EFNA2, EPLG6, LERK6
Antigen Type: Synthetic Peptide
Antigen Type: EFNA2
Gene ID: 1943
Primary Accession: O43921
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