EGF polyclonal, anti-human

Quantity: 100 µg

Background:
EGF is known as epidermal growth factor. This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. Additionally, it acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Description:
Rabbit IgG polyclonal antibody for Pro-epidermal growth factor (EGF) detection. Tested with WB, ELISA in Human.

Synonyms:
Beta urogastrone antibody, EGF antibody, Egf antibody, EGF_HUMAN antibody, Epidermal Growth Factor antibody, Epidermal Growth Factor antibody, HOMG4 antibody, OTTHUMP00000219721 antibody, OTTHUMP00000219722 antibody, Pro epidermal growth factor antibody, URG antibody, Urogastrone antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human EGF recombinant protein (Position: N971-R1023). Human EGF shares 69.8% amino acid (aa) sequence identity with both mouse and rat EGF.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.