EGFR (Epidermal Growth Factor Receptor) (clone B1D8), anti-human
€0.00
In stock
SKU
ARP-24-1956-MSM2
Catalog Number: 24-1956-MSM2
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2a, kappa
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2a, kappa
Decription:
This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin.
Synonyms: Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5
Clone: B1D8
Isotype: Mouse IgG2a, kappa
Immunogen: Microsomes from A431 cells.
Reactivity: human. Does not react with mouse and rat. Others-not known.
Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: Affinity Purification (For coupling, order Ab without BSA)
Blocks Ligand-induced Activation of EGFR
Inhibits Proliferation of A431 Cells (Order Ab without sodium azide)
Arrests Tumor Growth in vivo (Order Ab without BSA &Azide)
Immunoprecipitation (1-2 �g/500ug protein Lysate)
Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Optimal dilution for a specific application should be determined.
Reactivity: A431 cells, Breast or Bladder cancer
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin.
Synonyms: Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5
Clone: B1D8
Isotype: Mouse IgG2a, kappa
Immunogen: Microsomes from A431 cells.
Reactivity: human. Does not react with mouse and rat. Others-not known.
Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: Affinity Purification (For coupling, order Ab without BSA)
Blocks Ligand-induced Activation of EGFR
Inhibits Proliferation of A431 Cells (Order Ab without sodium azide)
Arrests Tumor Growth in vivo (Order Ab without BSA &Azide)
Immunoprecipitation (1-2 �g/500ug protein Lysate)
Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Optimal dilution for a specific application should be determined.
Reactivity: A431 cells, Breast or Bladder cancer
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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