EGFR (ErbB1) polyclonal (N-term), anti-human

EGFR (ErbB1) polyclonal (N-term), anti-human

€0.00
In stock
SKU
AC-AP7628a
Catalog Number: AC-AP7628a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1460
Applications: WB, IHC-P
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Background:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Other Names:
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1

Target/Specificity:
This EGFR (ErbB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-57 amino acids from the N-terminal region of human EGFR (ErbB1).

Antigen Region:
27-57

Antigen Type: Synthetic Peptide

Gene Name: EGFR (HGNC:3236)
Gene ID: 1956
Primary Accession: P00533
NCBI Accession: NP_005219.2;NP_958439.1;NP_958440.1;NP_958441.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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