EGFR polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Synonyms: ERBB, ERBB1, HER1, mENA, NISBD2, PIG61

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human EGFR

Gene Symbol: EGFR

Gene ID: 1956

Swiss prot: P00533

Calculated MW: 120kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.