EGFR-S1026 polyclonal (C-term), anti-human

EGFR-S1026 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP5436a
Catalog Number: AC-AP5436a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26905
Applications: WB, FC, IHC-P
Datasheet

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Background:
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Other Names:
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1

Target/Specificity:
This EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1004-1033 amino acids from the C-terminal region of human EGFR-S1026.

Antigen Region:
1004-1033

Antigen Type: Synthetic Peptide

Gene Name: EGFR (HGNC:3236)
Gene ID: 1956
Primary Accession: P00533
NCBI Accession: NP_005219.2;NP_958439.1;NP_958440.1;NP_958441.1
Other Accession: NP_958440.1;NP_005219.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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