EGLN1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP18620b
Background:
The protein encoded by this gene catalyzes thepost-translational formation of 4-hydroxyproline inhypoxia-inducible factor (HIF) alpha proteins. HIF is atranscriptional complex that plays a central role in mammalianoxygen homeostasis. This protein functions as a cellular oxygensensor, and under normal oxygen concentration, modification byprolyl hydroxylation is a key regulatory event that targets HIFsubunits for proteasomal destruction via the von Hippel-Lindauubiquitylation complex. Mutations in this gene are associated witherythrocytosis familial type 3 (ECYT3).
Other Names:
Egl nine homolog 1, Hypoxia-inducible factor prolyl hydroxylase 2, HIF-PH2, HIF-prolyl hydroxylase 2, HPH-2, Prolyl hydroxylase domain-containing protein 2, PHD2, SM-20, EGLN1 (HGNC:1232), C1orf12
Gene Name: EGLN1 (HGNC:1232)
Gene ID: 54583
Primary Accession: Q9GZT9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene catalyzes thepost-translational formation of 4-hydroxyproline inhypoxia-inducible factor (HIF) alpha proteins. HIF is atranscriptional complex that plays a central role in mammalianoxygen homeostasis. This protein functions as a cellular oxygensensor, and under normal oxygen concentration, modification byprolyl hydroxylation is a key regulatory event that targets HIFsubunits for proteasomal destruction via the von Hippel-Lindauubiquitylation complex. Mutations in this gene are associated witherythrocytosis familial type 3 (ECYT3).
Other Names:
Egl nine homolog 1, Hypoxia-inducible factor prolyl hydroxylase 2, HIF-PH2, HIF-prolyl hydroxylase 2, HPH-2, Prolyl hydroxylase domain-containing protein 2, PHD2, SM-20, EGLN1 (HGNC:1232), C1orf12
Gene Name: EGLN1 (HGNC:1232)
Gene ID: 54583
Primary Accession: Q9GZT9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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