EGR1 Polyclonal Antibody

Background:
EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
AT225, Early growth response 1, Early growth response protein 1, EGR 1, EGR-1, EGR1, EGR1, G0S30, KROX 24, KROX24, Nerve growth factor-induced clone A, Nerve growth factor-induced protein A, NGFI-A, NGFIA, TIS8, Transcription factor ETR103, Transcription factor Zif268, ZIF 268, ZIF268, Zinc finger protein 225, Zinc finger protein Krox-24, ZNF225

Immunogen: Recombinant protein of human EGR1

Swissprot: P18146
Gene Accession: BC073983

Calculated MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20689/sc-110/sc-189