EHMT1 (EUHMTASE1) polyclonal (Center), anti-human
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In stock
SKU
AC-AP1074b
Catalog Number: AC-AP1074b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5751
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5751
Applications: WB
Datasheet
Request Information
Background:
EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
Other Names:
Histone-lysine N-methyltransferase EHMT1, 211-, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Lysine N-methyltransferase 1D, EHMT1, EUHMTASE1, GLP, KIAA1876, KMT1D
Target/Specificity:
This EHMT1 (EUHMTASE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 979-1010 amino acids from the Central region of human EHMT1 (EUHMTASE1).
Antigen Region:
979-1010
Antigen Type: Synthetic Peptide
Gene Name: EHMT1
Gene ID: 79813
Primary Accession: Q9H9B1
NCBI Accession: NP_001138999.1;NP_079033.4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
Other Names:
Histone-lysine N-methyltransferase EHMT1, 211-, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Lysine N-methyltransferase 1D, EHMT1, EUHMTASE1, GLP, KIAA1876, KMT1D
Target/Specificity:
This EHMT1 (EUHMTASE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 979-1010 amino acids from the Central region of human EHMT1 (EUHMTASE1).
Antigen Region:
979-1010
Antigen Type: Synthetic Peptide
Gene Name: EHMT1
Gene ID: 79813
Primary Accession: Q9H9B1
NCBI Accession: NP_001138999.1;NP_079033.4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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