EIF2A monoclonal, anti-human, mouse, rat
€0.00
In stock
SKU
AC-AM8703b
Catalog Number: AC-AM8703b
Size: 50 µl, 200 µl
Isotype: mouse IgG2b,k
Clone Name: 1763CT191.40.42
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG2b,k
Clone Name: 1763CT191.40.42
Applications: WB
Datasheet
Request Information
Background:
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Other Names:
Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A
Target/Specificity:
This EIF2A antibody is generated from a mouse immunized with a recombinant protein of human EIF2A.
Antigen Type: Recombinant Protein
Gene Name: EIF2S1 (HGNC:3265)
Gene ID: 1965
Primary Accession: P05198
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Other Names:
Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A
Target/Specificity:
This EIF2A antibody is generated from a mouse immunized with a recombinant protein of human EIF2A.
Antigen Type: Recombinant Protein
Gene Name: EIF2S1 (HGNC:3265)
Gene ID: 1965
Primary Accession: P05198
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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