EIF2AK1 Polyclonal Antibody

Background:
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
E2AK1, EC 2.7.11.1, Eif2ak1, Eukaryotic translation initiation factor 2 alpha kinase 1, Eukaryotic translation initiation factor 2-alpha kinase 1, HCR, Heme controlled repressor, Heme regulated eukaryotic initiation factor eIF 2 alpha kinase, Heme regulated inhibitor, Heme regulated initiation factor 2 alpha kinase, Heme regulated repressor, Heme sensitive initiation factor 2a kinase, Heme-controlled repressor, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor, Hemin sensitive initiation factor 2 alpha kinase, Hemin-sensitive initiation factor 2-alpha kinase, HRI, KIAA1369, PRO1362

Immunogen: Fusion protein of human EIF2AK1

Swissprot: Q9BQI3
Gene Accession: BC006524

Calculated MW: 71 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.78 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.