EIF2AK2 (clone 3A10F7), anti-human

EIF2AK2 (clone 3A10F7), anti-human

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In stock
SKU
BT-MCA2678
Catalog Number: BT-MCA2678
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, FCM
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Background:
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Research Area: Signal Transduction

Synonyms: PKR, PRKR, EIF2AK1

Immunogen: Purified recombinant fragment of human EIF2AK2 (AA: 329-551) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage
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