Eif2ak2 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms: EIF2AK1, PKR, PPP1R83, PRKR

Cellular Location: Cytoplasm Nucleus perinuclear region

Immunogen:
Recombinant protein of human Eif2ak2

Gene Symbol: Eif2ak2

Gene ID: 5610

Swiss prot: P19525

Calculated MW: 62kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.