EIF2AK3 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP14551A
Catalog Number: AC-AP14551A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34502
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34502
Applications: WB, IHC-P
Datasheet
Request Information
Background:
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Other Names:
Eukaryotic translation initiation factor 2-alpha kinase 3, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK
Target/Specificity:
This EIF2AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-102 amino acids from the N-terminal region of human EIF2AK3.
Antigen Region:
73-102
Antigen Type: Synthetic Peptide
Gene Name: EIF2AK3
Gene ID: 9451
Primary Accession: Q9NZJ5
NCBI Accession: NP_004827.4
Other Accession: NP_004827.4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Other Names:
Eukaryotic translation initiation factor 2-alpha kinase 3, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK
Target/Specificity:
This EIF2AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-102 amino acids from the N-terminal region of human EIF2AK3.
Antigen Region:
73-102
Antigen Type: Synthetic Peptide
Gene Name: EIF2AK3
Gene ID: 9451
Primary Accession: Q9NZJ5
NCBI Accession: NP_004827.4
Other Accession: NP_004827.4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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