eIF2B Delta polyclonal antibody, anti-human, mouse, rat

Background:
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) is the fourth, or delta, subunit. Defects in EIF2B4 are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for EIF2B4.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: EIF2B4, EIF2BD, Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year