EIF2S3 polyclonal, anti-human, rat
€388.00
In stock
SKU
BS7910
Background:
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2α, eIF2β and eIF2γ (eukaryotic translation initiation factor 2 α, β and γ, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2S3 (eukaryotic translation initiation factor 2, subunit 3), also known as eIF2G, is a 472 amino acid protein that belongs to the γ subfamily of GTP-binding elongation factor proteins. Existing as a heterotrimer composed of an α, β and γ chain, eIF2S3 functions to bind ribosomal subunits and catalyze the subsequent formation of preinitiation complexes necessary for protein synthesis.
Alternative Name:
Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 2 subunit gamma X, eIF-2-gamma X, eIF-2gX, :EIF2S3, EIF2G
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: EIF2S3 polyclonal antibody detects endogenous levels of EIF2S3 protein.
Immunogen:
Recombinant full length Human EIF2S3.
MW: ~ 51 kDa
Swis Prot.: P41091
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2α, eIF2β and eIF2γ (eukaryotic translation initiation factor 2 α, β and γ, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2S3 (eukaryotic translation initiation factor 2, subunit 3), also known as eIF2G, is a 472 amino acid protein that belongs to the γ subfamily of GTP-binding elongation factor proteins. Existing as a heterotrimer composed of an α, β and γ chain, eIF2S3 functions to bind ribosomal subunits and catalyze the subsequent formation of preinitiation complexes necessary for protein synthesis.
Alternative Name:
Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 2 subunit gamma X, eIF-2-gamma X, eIF-2gX, :EIF2S3, EIF2G
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: EIF2S3 polyclonal antibody detects endogenous levels of EIF2S3 protein.
Immunogen:
Recombinant full length Human EIF2S3.
MW: ~ 51 kDa
Swis Prot.: P41091
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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